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Contraindicated (one)pentobarbital will decrease the extent or result of lorlatinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will reduce the extent or outcome of meloxicam by affecting hepatic enzyme CYP2C9/10 metabolism. Minor/Significance Unfamiliar.pentobarbital will lower the extent or impact of eltrombopag by infl